Naltrexone is used in high doses (25mg+) to treat alcoholism and opioid addiction since in 1980’s. In low doses (0.5mg – 10mg) naltrexone provides a wide variety of benefits ranging from craving management, to pain reduction, to sleep. Naltrexone is a non-controlled substance that can provide a variety of benefits without being habit forming.
Naltrexone is composed of a 50:50 mixture of the isomers Levo-Naltrexone and Dextro-Naltrexone.
The Levo is responsible for blocking opioid receptors – Increase endorphin release → modulate the immune system and reduce growth of unwanted cells.
The Dextro blocks receptors on immune cell – Block “TLR” on brain “glial” cells→ suppress production of inflammatory messengers and reduce inflammation, potentially downregulate oncogenes.